News:

  • 2024/03/21:

    Further insight into the function of an AsLOV2-FMN based singlet oxygen production provieded through a great collaboration with Erik Sedlak. Now published in Protein Science

  • 2024/03/08:

    Fantastic news - our collaboration with the Haitin group (Yoni and Moshe) brought surprising insights into the function of enigmatic intracellular chloride channels. And the sweet reward - the story made it to Nat Commun!

  • 2024/03/06:

    We have two more PhD position available. One on structural mass spec of prion proteins and membrane transporters and the other on clinical mass scpetrometry and method development. Apply till Apr 20!

  • 2024/03/04:

    Big welcome to Petr Jerabek. He has joined our group as a programmer and will help us with the development of fancy tools for MS data analysis in collaboration with Bruker.

  • 2024/02/14:

    We have a new visitor in our lab - Francesca Del Cioppo from the Uni Roma.

  • 2024/01/26:

    🕷🕷🕷Our lab ZOO is growing again. Mike's successor has just arrived! Welcome ❤ Mike II.

  • 2024/01/20:

    In 2023 we spent a lot of time working on different projects with Angel L. Pey from Uni of Grenada. Now the results are coming out. First one on AGT1 mutants is published in FEBS Lett. Thanks INSTRUCT and CIISB for support.

  • 2024/01/18:

    We are looking for PhD students! Position funded for 4 years in the field of structural MS and cool FT-MS top-down analysis - details here.

  • 2024/01/17:

    The last piece of Marok's PhD thesis puzzle is now in Anal. Chem. Well done Marok!

  • 2024/01/13:

    Welcome Honza and enjoy fun with structural mass spec!

Horizon 2020
EPIC-XS
EU FT-ICR MS MSCA

Important:

Structural characterization of biologicals and membrane proteins - Free EPIC-XS Online Workshop, February 9, 14:45-17:50 CET, 2023

Logo EPIC-XSEU Flag

The European Proteomics Infrastructure Consortium providing Access (EPIC-XS) consists of a unified network of experienced access providers and research groups who share a common goal: to facilitate the development and sustainability of proteomics exploration to all life science researchers within the European Union.

EPIC-XS has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 823839.

Speakers

Topics

  • Structural mass spectrometry
  • Antibody structure
  • Transmembrane proteins
  • Computational approaches

Program

Will be updated but spekaers are confirmed and timing settled

14:45 - 14:55
Participants joining, setting up connection
14:55 - 15:00
Welcome by chairperson, Michael Volny

Session 1 - ANTIBODIES

15:00 - 15:30
Introduction to antibody structure studies by mass spectrometry, Frank Sobott
15:30 - 15:50
Tuning HDX-MS pipeline for antibodies, Petr Man
15:50 - 16:10
Intact and top-down characterization of antibodies by high-resolution native MS, Maurits den Boer
16:10 - 16:20
Q&A with the three speakers moderated by Michael Volny
16:20 - 16:30
Break

Session 2 - TRANSMEMBRANE PROTEINS

16:30 - 17:00
Structural mass spectrometry of membrane proteins, Julian Langer
17:00 - 17:20
Radical labelling techniques applied to membrane proteins, Petr Novak
17:20 - 17:40
Probing the functional dynamics of native membrane proteins by HDX-MS, Argyris Politis
17:40 - 17:50
Q&A with the three speakers moderated by Michael Volny

Registration

The workshop is free but the registration is required. It is available HERE. The session will be hosted on Zoom platform.

The past 2022 EPIC-XS Webinars were a great success; don’t miss the event and join the 10th EPIC-XS Webinar on hot topics (antibodies and membrane proteins) in structural proteomics!

Organizers

  • Petr Novak
  • Petr Man
  • Michael Volny
  • Daniel Kavan