News:

  • 2024/11/27:

    Totally unexpected but we found a new cleavage preference in proteases cleaving primarily after proline (so-called PPCEs). These enzymes chew not only after Pro and Ala but also reduced Cys! Rewrite the textbooks! Also, this is the awaited first author paper of Zuza and the very first paper for Jasmin.

  • 2024/09/26:

    New group members! Welcome Ezgi, Sascha, Tomas. Also and some "old" ones starting their PhD (Jasmina and Michael)! Great to have you here!

  • 2024/09/26:

    Congratulations to Luky on completing the PhD Quest !🎉 👏Dr. Fojtik is now ready for his Sotio adventures. Good luck!

  • 2024/08/16:

    Our expertise in analyzing products of protein oxidation may help other research teams. Glad, we got just the enzyme and were not involved in the fight with termites.

  • 2024/07/09:

    FPOP+DIA+tims looks like a prowerful cocktail. Just published in Anal Chem! And a second step towards Marek's thesis.

  • 2024/06/04:

    🎉 Congratulations to Jasmina, Michal and Alex on successfully defending their diploma theses and completing the MSc degree. Well done!

  • 2024/05/22:

    🎉 Congratulations 👏 to DOCTOR Maroq! PhD thesis defended! Now, alligators 🐊 and magnets 🧲 are calling from Florida.

  • 2024/05/03:

    Time to harvest the fruits of Luky's PhD thesis. This time on the application of FFAP in epitope mapping. Czech the recent Anal. Chem. contribution.

  • 2024/04/16:

    Inspiring and long-lasting collaboration with Daniel Khananshvili and Moshe Giladi from the Tel Aviv University on Na+/Ca2+ exchangers resulted in a nice joint paper in Commun Biol. Thank you guys for your hard work and persistence!

  • 2024/04/15:

    The 15th EFTMS workshop will start soon - on Wed, Apr 17, 2024. Dont miss the lecture of prof. Michael L. Gross lecture available also online. Check here.

Horizon 2020
EPIC-XS
EU FT-ICR MS MSCA

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About laboratory



Laboratory of Structural Biology and Cell Signaling consists of a multidisciplinary team whose thematic focus is divided into two main directions. Structural biology group produces proteins by recombinant expression technologies and characterizes the protein or protein-ligand structures and their dynamics utilizing advanced mass spectrometric techniques. Cell signaling unit examines the linkages of cellular signaling to the metabolism of cancer cells using molecular biology and biochemistry methods. Through the collaboration of the two groups a unique research platform is formed, wherein the results obtained by the study of biological systems can also be verified and explained at the molecular level. Laboratory is located at the BIOCEV center in Vestec.

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